Biology 375

Concepts of Genetics

General Information

• Instructor: Dr. Rebecca L. Cann (Biomed A204, 956-6907)
• Lecture: M,W,F: 8:30 to 9:20 (Bilger 150)
• Discussion Section: M: (Biomed A108)
• Text: Concepts of Genetics (3rd edition) by W. S. Klug and M. R. Cummings
• Optional Student Handbook: A guide to concepts and problem solving for Concepts of Genetics (3rd edition) by H. Nickla
• Note: cross listed as GENE 451
• Note: was BIOL 451

Lecture Topics

• Introduction
• Cell divisions
• Life history in the cell
• Genetics, the old and new way
• Probability in genetics
• Variability and its functions
• Multiple alleles, interactions
• Gene interactions, norms
• Sex in model systems
• Sex-linkage characteristics
• Sexual selection
• Chromosome linkage
• Multiple crossovers
• Analysis of genetic maps
• Chromosome mutations (2X)
• Exam 1
• DNA #1: film and introduction
• DNA #2: structure
• Technologies with nucleic acids
• Replication and synthesis
• Control, synthesis, recombination
• Genetic code
• RNA, transcription
• RNA, translation and proteins
• Genes from nucleic acid pers.
• Proteins, structure, function
• Mutations and DNA
• Mutations and repair
• Genes in microbes
• Virus, plasmid genes
• Recombinant DNA introduction
• Biotechnology in the 1990s
• DNA organization, prokaryotes
• DNA and organelles
• Eukaryotic DNA organization
• Fine structure of genes
• DNA fingerprinting
• Bacterial gene regulation
• Eukaryotic regulation
• Developmental genetics
• Polygenic regulation
• Populations and evolution
• Final Exam